However, the Animal Medicinal Drug Use Clarification Act gives veterinarians the same kind of discretionary authority available to physicians, allowing veterinarians, under certain conditions, to prescribe an approved human or animal drug for “extra-label” uses, which are uses not listed on the label. Sometimes there may not be an approved animal drug available in the concentration or formulation needed for a specific patient. Other NSAIDs are available in the United States for people but have not been approved for dogs or cats. *Indicates an FDA-approved generic animal drug. Marketed under multiple brand and generic namesĭERAMAXX, DOXIDYL *, DERACOXIB CHEWABLE TABLETS * In the United States, currently marketed NSAIDs approved for dogs and cats include: However, clinical and experimental data suggest that NSAIDs also reduce inflammation through additional mechanisms of action, but they aren’t fully understood yet. The main mechanism of action of NSAIDs is to mediate the production or function of prostaglandins. When cells are damaged, they produce several substances, including prostaglandins. Inflammation-the body’s response to irritation or injury-is characterized by redness, warmth, swelling, and pain in the inflamed area. Additionally, dogs and cats of all ages undergo surgical procedures and FDA has approved several NSAIDs for dogs and two for cats to control postoperative pain and inflammation. FDA has approved several NSAIDs for dogs to control pain and inflammation associated with OA. With active lifestyles that extend into advanced age, many dogs are diagnosed with osteoarthritis (OA). Veterinarians are in the best position to inform dog and cat owners about these side effects and should discuss the benefits as well as the risks of an NSAID with their client before prescribing it for a patient.ĭogs are living longer and healthier lives thanks to advances in veterinary medicine and pharmaceuticals. ![]() ![]() ![]() Nonsteroidal anti-inflammatory drugs (NSAIDs) are a mainstay of pain management, but these drugs can cause side effects, some of which can be serious. Recognizing and controlling pain in dogs and cats are important parts of companion animal medicine.
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