![]() Microscopic nail clipping findings in patients with psoriasis. Microscopic examination of normal nail clippings. These cases were compared with data from two previous publications on normal nails and UPso, performed under the same collection methodologies, processing and terminologies, and evaluated by the same dermatopathologist. METHODSĪ cross-sectional study was conducted on cases of onychomycosis analyzed using clippings collected between September 2014 and February 2015. The objective of this study was to compare clippings of onychomycosis with published data on normal nails and ungual psoriasis (UPso). How the Nail Clipping helps the dermatologist. Diagnostic applications of nail clippings. 2017 21:525-39.Ģ Ghannoum MA, Hajjeh RA, Scher R, Konnikov N, Gupta AK, Summerbell R, et al A large-scale North-American study of fungal isolates from nails: the frequency of onychomycosis, fungal distribution, and antifungal susceptibility patterns. Onychomycosis in the 21st century: an update on diagnosis, epidemiology, and treatment. The correct diagnosis is essential, and clipping stained with Periodic Acid-Schiff (PAS) is very useful in these investigations. ![]() Onychomycosis corresponds to 50% of nail disorders, and the main differential diagnosis is nail psoriasis. Mycology Nail diseases Onychomycosis Pathology Psoriasis Conclusion:Ĭlipping helps in the differential diagnosis of onychomycosis and nail psoriasis and may be useful even when fungi are not found. The nail transition zone is more commonly blurred and irregular in onychomycosis. Onychocariosis is less common in psoriasis, while bacteria are more frequent. In onychomycosis, measurement of subungual region, serous lakes, neutrophils and number of layers of parakeratosis are more intense than in psoriasis. Sixty-two onychomycosis samples were compared with 30 normal nails and 50 nails with psoriasis. Methods:Ĭross-sectional study of onychomycosis cases, analyzed by clipping and compared with data on normal nails and those with nail psoriasis. The objective of this study was to compare the microscopic findings, other than the presence of fungi, in the clipping of onychomycosis versus normal nails and nail psoriasis. The main differential diagnosis is nail psoriasis. Of all nail disorders seen in dermatology offices, half of them are due to onychomycosis.
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